Black holes with non-minimal derivative coupling

We study the gravitational field equations in the presence of a coupling between the derivative of a massless scalar field and the Einstein tensor. This configuration is motivated by Galileon gravity as it preserves shift invariance in the scalar sector. We analytically obtain solutions with static and spherically symmetric geometry, which also include black holes with a single regular horizon. We examine the thermodynamical properties of these solutions, and we reveal the non-perturbative nature of the Galileon coupling constant. We also find a phase transition, similar to the one described by Hawking and Page, which occurs at a critical temperature determined by both the black hole mass and by the strength of the coupling.Comment: Matches the published versio

Dual-use Molecules from Yeast

This year the OPCW, the implementing body for the Chemical Weapons Convention, celebrates the 20th anniversary of entry into forces. In 2014, this organization examined the impact of new technologies in the field of chemical and biological weapons, in particular the “Convergence” of Chemistry and Biology. An OPCW report of the Scientific Advisory Group highlighted the importance of monitoring developments in science and technology: “New production processes, combined with developments in drug discovery and delivery, could be exploited in the development of new toxic chemicals that could be used as weapons.” 1 Indeed, since 2008, Synthetic Biology is monitored also by other international organizations, such as the Nonproliferation Export Control Regimes Australia Group

Unified Scenario for Composite Right-Handed Neutrinos and Dark Matter

We entertain the possibility that neutrino masses and dark matter (DM) originate from a common composite dark sector. A minimal effective theory can be constructed based on a dark $SU(3)_D$ interaction with three flavors of massless dark quarks; electroweak symmetry breaking gives masses to the dark quarks. By assigning a $\mathbb Z_2$ charge to one flavor, a stable "dark kaon" can provide a good thermal relic DM candidate. We find that "dark neutrons" may be identified as right handed Dirac neutrinos. Some level of "neutron-anti-neutron" oscillation in the dark sector can then result in non-zero Majorana masses for light Standard Model neutrinos. A simple ultraviolet completion is presented, involving additional heavy $SU(3)_D$-charged particles with electroweak and lepton Yukawa couplings. At our benchmark point, there are "dark pions" that are much lighter than the Higgs and we expect spectacular collider signals arising from the UV framework. This includes the decay of the Higgs boson to $\tau \tau \ell \ell^{\prime}$, where $\ell$($\ell'$) can be any lepton, with displaced vertices. We discuss the observational signatures of this UV framework in dark matter searches and primordial gravitational wave experiments; the latter signature is potentially correlated with the $H \to \tau \tau \ell \ell^{\prime}$ decay.Comment: 8 pages, 4 figures, 1 table. Version published on PR

Self-T-Dual Brane Cosmology and the Cosmological Constant Problem

We consider a codimension-one brane embedded in a gravity-dilaton bulk action, whose symmetries are compatible with T-duality along the space-like directions parallel to the brane, and the bulk time-like direction. The equations of motions in the string frame allow for a smooth background obtained by the union of two symmetric patches of AdS space. The Poincar\'{e} invariance of the solution appears to hold independently of the value of the brane vacuum energy, through a self-tuning property of the dilaton ground state. Moreover, the effective cosmology displays a bounce, at which the scale factor does not shrink to zero. Finally, by exploiting the T-duality symmetry, we show how to construct an ever-expanding Universe, along the lines of the Pre-Big Bang scenario.Comment: Minor corrections, comments & references added. Accepted for publicatio

Model Fisik Kincir Air untuk Irigasi Pertanian

Physical model research of water wheel for agricultural irrigation is executed at Hidrotechnic's Laboratory University of Riau. Model that is utilized doesn't utilize model scale, but phenomenon of prototype will be represented by model that made. Water wheel bases executed field study previous, having alone uniqueness. Paddle wheel lap speed one every minute (RPM) and debit who can be lifted by waters jacking tube visual's are relative stable. Even so was known it must be water wheel condition be still get improved debit that can be lifted by waters jacking tube. Water wheel model is undershoot water wheel made bases prototype aught at the site or at agricultural location. This waterwheel is made at Technicals Engineering Material Laboratory. This Waterwheel model specification with diameter 55 cm, broad 6 cm, long fan 6 cm, total fan 18 numbers and heavy 1,764 kg. The research did by variated foots up and tube dimension so gotten by water wheel model with tubed optimal one. Variation of tube is 3, 6, 9 and 18 numbers with each volume saves 3,4 ml, 8,0 ml, and 16,8 ml whereas debit flows are not variated.Result of this experiment showing that Waterwheel speed regarde by flow speed that punches waterwheel fans, but relationship both is not linear. Total tube and tube volume regard paddle wheel lap. Diameter 0,8 cm tube can't lift waters because the diameter of tube are too small but diameter 1,3 cm and 1,7 cm tube both can lift flows.Maximum debits which diameter 1,3 tube can be lifted by jacking tube is 6,39 ml/dt, it happens upon tube amount 18 numbers whereas on diameter tube 1,7 cm maximum debits is 5,38 ml / dt happens upon tubed amount 6 numbers

Brane World in a Topological Black Hole Bulk

We consider a static brane in the background of a topological black hole, in arbitrary dimensions. For hyperbolic horizons, we find a solution only when the black hole mass assumes its minimum negative value. In this case, the tension of the brane vanishes, and the brane position coincides with the location of the horizon. For an elliptic horizon, we show that the massless mode of Randall-Sundrum is recovered in the limit of large black hole mass.Comment: Latex, 8 pages, v2: Additional references, to appear in MPL

The Human SLC25A33 and SLC25A36 Genes of Solute Carrier Family 25 Encode Two Mitochondrial Pyrimidine Nucleotide Transporters

The human genome encodes 53 members of the solute carrier family 25 (SLC25), also called the mitochondrial carrier family, many of which have been shown to transport inorganic anions, amino acids, carboxylates, nucleotides, and coenzymes across the inner mitochondrial membrane, thereby connecting cytosolic and matrix functions. Here two members of this family, SLC25A33 and SLC25A36, have been thoroughly characterized biochemically. These proteins were overexpressed in bacteria and reconstituted in phospholipid vesicles. Their transport properties and kinetic parameters demonstrate that SLC25A33 transports uracil, thymine, and cytosine (deoxy)nucleoside di- and triphosphates by an antiport mechanism and SLC25A36 cytosine and uracil (deoxy)nucleoside mono-, di-, and triphosphates by uniport and antiport. Both carriers also transported guanine but not adenine (deoxy)nucleotides. Transport catalyzed by both carriers was saturable and inhibited by mercurial compounds and other inhibitors of mitochondrial carriers to various degrees. In confirmation of their identity (i) SLC25A33 and SLC25A36 were found to be targeted to mitochondria and (ii) the phenotypes of Saccharomyces cerevisiae cells lacking RIM2, the gene encoding the well characterized yeast mitochondrial pyrimidine nucleotide carrier, were overcome by expressing SLC25A33 or SLC25A36 in these cells. The main physiological role of SLC25A33 and SLC25A36 is to import/export pyrimidine nucleotides into and from mitochondria, i.e. to accomplish transport steps essential for mitochondrial DNA and RNA synthesis and breakdown

TX Task: Automatic detection of focus organisms in biomedical publications

In biomedical information extraction (IE), a central problem is the disambiguation of ambiguous names for domain specific entities, such as proteins, genes, etc. One important dimension of ambiguity is the organism to which the entities belong: in order to disambiguate an ambiguous entity name (e.g. a protein), it is often necessary to identify the specific organism to which it refers. In this paper we present an approach to the detection and disambiguation of the focus organism(s), i.e. the organism(s) which are the subject of the research described in scientific papers, which can then be used for the disambiguation of other entities. The results are evaluated against a gold standard derived from IntAct annotations. The evaluation suggests that the results may already be useful within a curation environment and are certainly a baseline for more complex approaches

Analisis Pengetahuan Konseptual, Prosedural, dan Metakognitif Siswa Melalui Pembelajaran Integrasi Flipped Classroom dan PBL

Student-centered learning (SCL) is a learning approach that not only encourages to how student constructs their conceptual knowledge, but also to achieve the involvement of their knowledge in daily activity, in forms procedural and metacognitive knowledge. Flipped classroom learning models marked by reversed learning activities syntax between class and home, which promoted student to active self-learning, before turn into face to face class meeting. Problem Based Learning (PBL) model provides students to apply their knowledge to formulate strategy and solution in facing their problem. Flipped classroom or PBL, both are student-centered learning models that triggers student to self-constructed knowledge actively and student’s curiosity to solve their problem. This paper attempts to analyze the influence of integration flipped classroom and PBL on conceptual, procedural, and metacognitive knowledge on Linear Motion subject. This research is a quasi experimental model with post-test only control design. The population in this study were all students of class X MIPA SMA Negeri 37 Jakarta in the 2019-2020 school year. The sample in this study were students of class X MIPA 1 as the experimental class and class X MIPA 2 as the control class. The sample was taken using cluster sampling technique. The results obtained showed that the percentage of conceptual, procedural and metacognitive knowledge of the experimental class was 88.9%; 77.8%; and 88.9% which is higher than the control class with the respective percentage 66.7%; 55.8%; and 75%. The integration of the flipped classroom and PBL models can be applied to materials other than Linear Motion to improve conceptual, procedural, and metacognitive knowledge